Las mujeres casi nunca presentan dmdb, porque tienen dos cromosomas x. Pdf duchenne muscular dystrophy clinical presentation. It primarily affects males, but, in rare cases, can also affect females. Until the 1980s, little was known about the cause of any kind of muscular dystrophy. Grange, phd5 1wake forest institute for regenerative medicine, wake forest university, winstonsalem, north carolina 27157, usa. Duchenne muscular dystrophy is an xlink recessive disorder that affects 1 per 3. Summary duchenne muscular dystrophy dmd is an inherited progressive. In some older murine studies, evidence indicated that eccentric and highintensity exercise may result in decreases in muscle strength. In 1987, the protein associated with this gene was identified and named dystrophin. Becker muscular dystrophy is less common, affecting approximately 1 per 30 000 males. Caracterizase pela degeneracao progressiva e irreversivel da musculatura esqueletica, levando a uma fraqueza muscular generalizada, devido a ausencia da proteina distrofina na membrana muscular. O gene responsavel pela dmd foi isolado em 1986 e identificouse. Summary duchenne muscular dystrophy dmd is an inherited progressive disorder, a chromosome xlinked recessive trait. The diagnosis and management of duchenne muscular dystrophy, part 1.
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